Frequently Asked Questions


Are any biological agents added to the stem cells such as medications or mixtures containing Plasma Enriched Platelets?

Our adipose derived stem cell gathering and isolation technique yields enormously high amounts of stem cells. In examining conclusions data, treatment cell numbers appear to identify with treatment success. Our cells are really in a kind of soup called Stromal Vascular Fraction SVF which is stem cells washed in a rich mixture of natural growth factors (Not the same as human growth factor hormone which is only one type of growth factor). Some sorts of orthopedic and urologic diseases appear to respond better to stem cells that are super enriched with development factors made by administering Platelet Rich Plasma to the patient. Autologous Platelet Rich Plasma is procured from a patient’s own blood drawn at the time of deployment. At RMIN we don’t include any foreign substances or medicines to the stem cells.

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Are any patients automatically excluded?

Yes. Patients with uncontrolled cancer are prohibited. If you have an active infection anywhere in your body you must be treated first. Extremely sick patients may require special consideration. Also, anybody with a bleeding disorder or who takes blood thinning medicines requires unique assessment before consideration for stem cells.

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Are there reports of autologous adipose derived adult mesenchymal stem cells harming any humans or animals?

We know of no recorded cases directly or in the literature where serious harm has come about. All of our patients will be entered into a database to collate and report any adverse responses. This data is key to the advancement of stem cell science. There have been a couple of reports of serious complications from overseas and these are continuously completely assessed by epidemiologists to discover the facts. The International Stem Cell Society registry has over 1,000 cases presently registered and just 2% of the treatments were connected with any complications, none of which were considered “serious adverse events.”

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Can extra stem cells be saved for future use should an immediate need arise?

Stem cells might be cryopreserved as liposuction fat for prolonged periods of time. Currently, this service is being considered for outsourcing to an outside supplier known who have rigorous quality control. Numerous patients have been asking about banking cells while they are still young since stem cell numbers drop regularly with every decade of life and some advocate getting and saving cells to be utilized later within life as needed. (see chart).

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Can I be expected to improve after stem cell treatment at RMIN?

Distinctive conditions are treated in diverse ways and there are distinctive degrees of success. Assuming that the objective is regeneration of joint cartilage, one may not see wanted results until some months after treatment. A few patients may not experience significant change and others might see dramatic regeneration of damaged tissue or resolution of disease. Many of the disorders and issues that the doctors at RMIN are treating represent pioneering work and there is an absence of information. FDA regulations prevent RMIN from making any claims about desires for success, on the other hand, in the event that you are picked for treatment, it will be explained that we believe stem cell therapy may be beneficial or in a few cases that we are unsure and treatment might be considered investigational.

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Can stem cells cause cancer?

Adult mesenchymal stem cells are not known to cause cancer. A few patients have known about stories of cancer caused by stem cells, however these are likely identified with the utilization of embryonic cells (Not Adult Mesenchymal Cells). These embryonic tumors known to be teratomas are uncommon but possible occurrences when embryonic cells are utilized.

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Can stem cells treat cancer?

No. Large groups are confused by this because they have become aware of cancer patients receiving “stem cell transplants.” These patients had ablative bone marrow therapy and require stem cells to re-populate their blood and marrow. This is not quite the same as the stem cells we send to treat noncancerous human diseases at RMIN.

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Cell Banking

We are currently setting up FDA approved locations for stem cell banking in a joint effort with a trustworthy cryo-technology organization. This empowers an individual to get autologous stem cells at whatever time in the future without needing to experience liposuction again may be inconvenient or contraindicated. Having your own stem cells accessible for medical immediate utilization is a significant medical asset.

Provisions are almost set up for this choice and storage of your own stem cells acquired by liposuction at RMIN or from fat obtained from cosmetic procedures performed somewhere else ought to be conceivable within the near future

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Does a candidate have to participate in research to receive treatment at RMIN?

No. Participation in any of our protocols is not mandatory and there are no incentives, financial or otherwise, to induce patients to enroll in our studies. In any case, RMIN is committed to clinical research for the improvement of stem cell science. RMIN is taking a dynamic part in cutting edge clinical research in the new field of regenerative medicine. Research studies will be explained and privacy will be maintained. Formal future research studies will be managed by an Institutional Review Board which is an authorized agency that promotes validity, transparency and protection of human study enrollees .

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Does RMIN use any embryonic stem cells?

No. Just adult mesenchymal stem cells are utilized. These cells are capable of forming bone, cartilage, fat, muscle, ligaments, veins, and certain organs. Embryonic stem cells are connected with moral contemplations and confinements.

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Does RMIN use stem cells from any other animal source or person?

No. Just an individual’s own adult autologous cells are utilized. These are collected from every individual and deployed back into their own body. There is no danger of contamination or danger of introduction of mammalian DNA into the treatments.

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How are the cells deployed into a patient?

How are the cells deployed?
Contingent upon the sort of treatment needed, stem cells could be infused through veins, arteries, into spinal fluid, subcutaneously, or straightforwardly into joints or organs. All of these are considered minimally invasive methods of introducing the stem cells. Stem cells infused intravenously are known to “search out and find” (see photograph) areas of tissue damage and relocate to that area possibly giving regenerative healing. Intravenously infused stem cells have been indicated to have the capability of crossing the “blood-brain barrier” to enter the central nervous system and they might be recognized in the patient’s body numerous months after deployment. Note yellow arrow indicating the stem cells concentrated in the patients hand where he had a Dupytrens contracture (Dupuytren’s contracture is a hand deformation that makes the tissue underneath the surface of the hand thicken and contract).

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How do adult stem cells heal?

These adult stem cells are known as “progenitor” cells. This means they remain dormant (do nothing) unless they witness some level of tissue damage. It’s the tissue damage that turns them on. Along these lines, when an individual has a degenerative type issue, the stem cells have a tendency to head off to that area of need and animate the healing process. We’re still not certain if they simply change into the sort of injured tissue required for repair or if they convey signs that prompts the repair by some other mechanism. Suffice it to say that there are various animal models and plenty of human experiences that shows these are huge reparative cells.

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How does RMIN control sterility in the processing of the stem cells?

Stem cells are harvested under sterile conditions utilizing an uncommon “closed system” technology with the intention that the cells never come into contact with the environment throughout the whole process from removal to deployment. Sterile method and antibiotics are additionally used to prevent infection.

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How is the fat obtained?

RMIN patients have their fat (typically love handle area) harvested in our special sterile treatment facility under a local anesthetic. The fat evacuation method lasts approximately twenty minutes. Specially designed equipment is utilized to gather the fat cells and less than 100cc of fat is needed. Post operative discomfort is minimal and there is insignificant limitation on movement.

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How long does it take to see improvement?

Stem cell therapy depends on the body’s own regenerative healing to happen. The regenerative methodology might take time, especially with orthopedic patients, who may not see results for a few months. In some diseases, more immediate reactions are possible.

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How many injections are required for success?

Most patients, particularly those with orthopedic conditions, require only one deployment. Certain sorts of degenerative conditions, especially auto-immune disease, might react best to a series of deployments rather than only one deployment. The number and need of any extra treatments would be chosen on a case by case basis. Financial consideration is given in these occasions.

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Is everyone a candidate?

No. Just certain medical issues are presently being treated at RMIN. Check our list or fill out a candidate application form on the website. All patients need to be medically stable enough to have the treatment in our office. There may be some uncommon conditions that may in the long run be treated in hospitalized patients, but that remains for the future. A few patients may be declined because of the severity of their problem. Different patients might not have conditions fitting to treat or may not be covered by our specialists or our protocols. A waiting list or outside referral (provided that we know of another person treating such an issue) could be pertinent in such cases.

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Is our procedure FDA-approved?

No. However, Regenerative Medicine Institute of Nevada’s strategies are part and parcel to the classification of doctor’s practice of medicine, wherein the physician and patient are allowed to consider their chosen course of treatment. The FDA does have guidelines about treatment and manipulation of a patient’s own tissues. At RMIN we meet these guidelines by providing same day treatment with the patient’s own particular cells that experience extremely negligible control and are embedded throughout the same procedure. Additionaly we are listed under the FDA clinical trial area.

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NonEmbryonic Adult Stem Cells

Adult (Nonembryonic) Mesenchymal Stem Cells are undifferentiated cells that can replace dying cells and regenerate harmed tissue. These unique cells search out areas of harm, disease and decimation where they are equipped for regenerating healthy cells and empowering an individual’s natural recuperating process to be quickened. As we gain a deeper comprehension of their therapeutic capacity and apply this learning, we are anticipating their tremendous remedial potential to help the body recuperate itself. Adult stem cells have been utilized for a mixture of medicinal medications to repair and recover intense and chronically harmed tissues in people and animals. The utilization of stem cells is not FDA approved for the treatment of any particular disease in the United States at this point and their utilization is still investigational. Numerous respectable worldwide centers have been utilizing stem cell therapy to treat different chronic degenerative conditions as assorted as intense neurologic diseases, renal failure, erectile dysfunction, degenerative orthopedic issues, and even cardiovascular and pulmonary diseases to name a couple. Adult stem cells seem to be especially viable at repairing cartilage in worsened joints.

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Once a candidate is selected for treatment, how does RMIN obtain a person’s stem cells?

Stem cells are harvested and purified throughout the same surgical setting. Our patients experience a minimally-invasive liposuction sort of harvesting methodology by a Board Certified plastic surgeon in our specialized treatment facility in Las Vegas. The gathering technique for the most part takes a few minutes and might be carried out under local anesthesia. Cells are then handled and are prepared for deployment inside 180 minutes or less.

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Our Technology

Regenerative Medicine Institute of Nevada utilizes fat derived stem cells for therapeutic & clinical exploration. Early stem cell research has generally been connected with the disputable utilization of embryonic stem cells. The new focus is on non-embryonic adult mesenchymal stem cells which are discovered in an individual’s own blood, bone marrow, and fat. Most stem cell treatment centers in the world are right now utilizing stem cells determined from bone marrow.

A recent technological breakthrough empowers us to now use fat sourced stem cells. Autologous stem cells from an individual’s own fat are not difficult to collect securely under local anesthesia and are abundant in amounts up to 2500 times those seen in bone marrow.

Clinical success and good conclusions appear to be related to the amount of stem cells conveyed. When these fat sourced stem cells are directed back into the patient, they have the possibility to repair human tissue by structuring new cell of mesenchymal origin, for example cartilage, bone, ligaments, tendons, nerve, fat, muscle, veins, and certain internal organs. Stem cells’ capability to form cartilage and bone makes them conceivably exceptionally promosing in the treatment of degenerative orthopedic conditions. Their capacity to form new blood vessels and smooth muscle makes them extremely advantageous in the treatment of ischemia or poor blood flow. Stem cells are utilized in Europe and Asia to treat these conditions.

We have anecdotal and experimental confirmation that stem cell therapy is viable in mending and recovery of chronic conditions. Stem cells search out harmed tissues to repair the body naturally. The medical journals and web are full of valuable testimonials however we are as of now anticipating conclusive studies showing viability of stem cell therapy. Such information might take five or ten years to amass. In an effort to provide easing for patients experiencing certain degenerative diseases that have been impervious to normal modalities of treatment, we are launching pilot studies as trial tests of treatment adequacy with exceptionally high amounts of adipose sourced stem cells obtained from fat. Adipose fat is an abundant and reliable source of stem cells.

Regenerative Medicine Institute of Nevada’s cell collecting and separation procedures are based upon technology from Korea. This new innovative leap forward permits patients to securely gain their own particular autologous stem cells in vast amounts. Our treatments and research are patient supported and we have attempted financially to make it reasonable. The entirety of our sterile methods are non-intrusive and done under local anesthesia. Patients who are searching for non-surgical alternatives to their degenerative issue can take part in our trials by filling out our treatment requisition to confirm that they are candidates. Regenerative Medicine Institute of Nevada is pleased to be state of the art in the new field of Regenerative Medicine.

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Some stem cell treatment centers make extraordinary claims about their success in the treatment of various problems. Why doesn’t RMIN?

RMIN is doing pioneer research and treatment of numerous diseases. All investigational information is continuously gathered so that results will be published in peer review medical journals and eventually used to advertise the advancement of cell based regenerative medicine. FDA regulations command that no publicizing medicinal cases be made and that even site testimonials are prohibited.

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What about patients with known cancers?

Stem cell therapy is thought to be safe and not influence dormant cancers. If somebody has had cancer that was treated and responded successfully, there is no reason to withhold stem cell deployment. In most cases, stem cells should not be utilized within patients with known active cancer.

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What are some diseases that RMIN is definitely not treating at this time?

At this point, we are not treating autism, spinal cord injuries, and some advanced diseases. See list of issues as of now being examined at RMIN.

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What are the tools of regenerative medicine?

Customarily, we have utilized different prescriptions and hormones to limit disease and help the body repair itself. For instance, hormone replacement therapy has, in many cases, indicated the capability to all the more optimally help the immune system and consequently help us repair diseased or harmed tissues. Genetic exploration is an advancing area where we will eventually learn and use more methods for explicitly managing gene defects causing degenerative disease. Stem cell therapy is an alternate quickly developing and exciting area that has as of recently indicated extensive guarantee in treating numerous degenerative conditions.

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What claims are currently made by RMIN about what stem cell therapy can do for you?

None. Our point is to make cell based medicine accessible to patients who are intrigued and to provide progressing research information under approved Institutional Review Board (IRB) accepted studies. We will follow our stem cell treatment patients over their lifetimes. This will empower us to accumulate noteworthy information about the different degenerative diseases we treat. Rather than providing basically anecdotal or testimonial data, our objective is to sort the different conditions and follow the patient’s progress through different objective (e.g. x-ray evidence or video displays) and subjective (e.g. patient and/or doctor surveys) criteria. We are familiar with a great deal of stories about marked improvement of a variety of conditions, yet we make no cases about the expected treatment. Sometime in the future, once sufficient amounts of information are gathered, it could be appropriate to submit the data to the FDA at which point a genuine case may be substantiated and distinguished by the Agency. Still, these are your own particular cells and not “medicine” available to be purchased. They are just being utilized in your own body. Most likely, no claim needs to be made; rather a measurable examination of our discoveries might suffice to suggest if treatments are legitimately and essentially adequate. We also hope to submit our patient’s information to an approved International Registry (See ICMS Stem Cell Registry)further encouraging substantial accumulations of information to help distinguish both positive and negative trends.

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What diseases and problems can be treated?

This will hinge on upon the sort of degenerative condition you have. An expert will assess you and examine if you’re a potential applicant for stem cell therapy. Provided that after you’ve been recommended for treatment, had a chance to comprehend the potential dangers and benefits, and chose on your own that you might want to investigate this avenue of treatment, then you could be accepted for treatment. Obviously, in spite of the fact that it is a minimally invasive procedure, you will still need to be medically cleared for the procedure.

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What does the cost of procedure include?

As a result of recent developments in technology, RMIN has the ability to give outpatient stem cell treatment at a portion of the expense of that seen in numerous overseas clinics. The fee covers fat cell harvesting, cell preparation, and stem cell deployment which might incorporate the utilization of advanced interventional radiology and fluoroscopy methods. Financing is accessible through a credit vendor.

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What is a stem cell?

A stem cell is fundamentally any cell that can reproduce and separate. This means the cell can not just increase, it can transform into distinctive types of tissues. There are various types of stem cells. Most individuals are acquainted with or have heard the expression “embryonic stem cell.” These are cells from the embryonic stage that have yet to separate – all things considered, they can change into anyone part whatsoever. These are then called “pluri-potential” cells. On the grounds that they are taken from unborn or unwanted embryos, there has been extensive controversy surrounding their utilization. Additionally, while they have been utilized as a part of a few areas of medicine – especially, outside the United States – they have likewise been connected with periodic tumor (teratoma) developments. There is work being directed by some organizations to confine specific lines of embryonic stem cells for future use.

Another kind of stem cell is the “adult stem cell.” This is a stem cell that already lives in one’s body inside distinctive tissues. Lately, much work has been carried out isolating bone-marrow derived stem cells. These are otherwise called “mesenchymal stem cells” in light of the fact that they hail from the mesodermal section of your body. They can separate into bone and cartilage, and likely all other mesodermal components, for example fat, connective tissue, blood vessels, muscle and nerve tissue. Bone marrow stem cells might be concentrated and since they are low in numbers, they are usually cultured with a specific end goal to increase their numbers for future utilization. It would appear, fat is also filled with mesenchymal stem cells. Actually, it has hundreds if not thousands of times more stem cells compared to bone marrow. Today, we actually have instruments that permit us to isolate the stem cells from fat. In light of the fact that most individuals have sufficient fat supplies and the amounts of stem cells are so incredible, there is no need to culture the cells over a period of days and they can be used right away.

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What is regenerative medicine?

Regenerative Medicine is the procedure of making living, useful tissues to repair or replace tissue or organ function lost because of harm, or congenital defects. This field holds the potential of regenerating harmed tissues and organs in the body by stimulating previously irreparable organs to mend themselves. (Wikipedia)

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What is the cost of consultation and treatment?

Patients who are considered to be candidates dependent upon data provided in the candidate application form will be invited for a conference with one of our panel physicians. A non-refundable expense of $250 is charged for this conference which incorporates office assessment (but may also include physicians assessment of X-Rays, records, or telephonic interviews). RMIN will apply this $250 towards the expense of the stem cell treatment procedure should the patient be chosen. Unfortunately, insurance won’t take care of the actual expense of stem cell treatment as a rule since stem cell therapy is still considered experimental. The expense differs hinging upon the disease state being treated and which sort of stem cell deployment is required.

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What types of specialties are represented at RMIN?

Urology, cosmetic surgery, ear, nose, & throat, orthopedics, inner medication and cardiology are represented. Arrangements are at present being made for various different specialties. Regenerative Medicine Institute of Nevada is the first multispecialty stem cell center in Nevada.

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Where can I get more information of stem cell treatments?

The International Cellular Medicine Society (ICMS) is a good resource. Stem Cells 101

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Who decides who is eligible?

The specialist seeing you at RMIN will make a determination dependent upon your history and exam, studies, and current research discoveries. Any complex cases may be inspected by our ethics advisory committee. Occasionally, we may seek opinions from thought leaders around the world.

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Why do patients request stem cell treatment?

Many have been told that they require surgery or other risky treatments for their ailments and are looking for non-invasive alternatives. Some have known about the compelling testimonials about stem cells in the medical journals and on different websites. Many have read about the outcomes of stem cell treatments in animal trials and in people. RMIN gives an option to those educated patients who look for present day regenerative therapy yet want comfort, quality and affordability. RMIN fills a need for those patients who have been led to believe they need to fly out to distinctive nations and pay as much as twenty to one hundred thousand dollars for stem cell treatments off shore. (See stem cell tourism).

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Why do some stem cell facilities around the world require days to weeks before removal of mesenchymal stem cells until reinsertion into the patient?

These facilities are getting stem cells from bone marrow or blood in generally minor amounts and they are then culturing (developing) the cells to make sufficient amounts. Research seems to indicate that success of treatment is directly related with the amount of cells infused. RMIN utilizes fat sourced stem cells that are abundant naturally at approximately 2,500 times levels found in bone marrow (the most well-known wellspring of mesenchymal stem cells). RMIN utilizes technology that isolates adipose stem cells in vast numbers in a brief time span so prolonged culturing is unnecessary and cells might be conveyed into a patient inside 90 minutes of gathering.

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Why does RMIN take a multispecialty treatment approach to regenerative medicine?

Patients experience the ill effects of numerous assortments of degenerative sicknesses. There may be conditions connected with nearly all parts of the body. Board Certified specialists are perfect to assess, prescribe or treat, and subsequently follow your progress. Together, through the RMIN, we work to facilitate and provide therapy – mainly with your own stem cells, additionally through different avenues of regenerative medication. This could incorporate hormone replacement therapy or other proper recommendations.

For example, assuming that you have a knee issue, you might see RMIN’s Board Certified orthopedic surgeon as opposed to a nonexclusive “clinic director.” Also, you could be recommended for assessment for hormone replacement therapy or an exercise program might be recommended for results to be optimal. Nonetheless, we believe stem cell therapy to be the likely foundation for regenerative treatment.
It should also be noted, that all treatments are as of now in the investigational stage. While we understand our patients are looking for development in their condition through stem cell therapy, every treatment is part of a progressing examination to create optimal parameters for treatment, to assess for viability and for any adverse effects. It is key that patients comprehend they are partaking in these investigational (exploration) analyses. When sufficient data is properly reported and measurably significant, then information (accepted by an Institutional Review Board) may be exhibited to the FDA for public documentation.

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Why does RMIN use liposuction fat rather than bone marrow as a source of stem cells?

Bone marrow harvesting (a sort of uncomfortable procedure) yields roughly 5,000 – 60,000 cells that are then cultured over a few days to maybe a couple of million units preceding utilization (infusion into the patient). Recent developments in stem cell science have made it conceivable to get high amounts of extremely high quality multi-potent (able to form numerous other tissues) units from an individual’s own liposuction fat. RMIN utilizes technology obtained from Asia to process this fat to yield approximately five hundred thousand to one million stem cells for every cc of fat, and subsequently, it is conceivable to obtain as many as 10 to 40 million cells from a solitary treatment. These adipose derived stem cells can transform into numerous diverse sorts of cells when conveyed properly including bone, cartilage, tendon (connective tissue), muscle, blood vessels, nerve tissue and others.

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